PrimePCR™ Probe Assay: FCGR2B, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: FCGR2B, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: FCGR2B, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0049587
Assay Design:   exonic
Chromosome Location:   1:161647328-161647427question
Amplicon Length:   70
Splice Variants Targeted:   ENST00000236937 ENST00000367961 ENST00000358671 ENST00000367962 ENST00000367960 ENST00000403078

Gene Information

The protein encoded by this gene is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. The encoded protein is involved in the phagocytosis of immune complexes and in the regulation of antibody production by B-cells. Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq Jun 2010]

Gene Symbol:   FCGR2B
Gene Name:   Fc fragment of IgG, low affinity IIb, receptor (CD32)
Aliases:   CD32, CD32B, FCG2, FCGR2, IGFR2
RefSeq:   NC_000001.10 NT_004487.19 NG_023318.1
Ensembl:   ENSG00000072694
Entrez:   2213
Chromosome Mapping:   1q23

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