PrimePCR™ Probe Assay: FBLN1, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: FBLN1, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: FBLN1, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0049669
Assay Design:   exonic
Chromosome Location:   22:45923790-45923880question
Amplicon Length:   61
Splice Variants Targeted:   ENST00000411478 ENST00000455233 ENST00000402984 ENST00000262722 ENST00000327858 ENST00000442170 ENST00000340923 ENST00000454279 ENST00000451475 ENST00000348697

Gene Information

Fibulin 1 is a secreted glycoprotein that becomes incorporated into a fibrillar extracellular matrix. Calcium-binding is apparently required to mediate its binding to laminin and nidogen. It mediates platelet adhesion via binding fibrinogen. Four splice variants which differ in the 3' end have been identified. Each variant encodes a different isoform but no functional distinctions have been identified among the four variants. [provided by RefSeq Jul 2008]

Gene Symbol:   FBLN1
Gene Name:   fibulin 1
Aliases:   FBLN, FIBL1
RefSeq:   NC_000022.10 NT_011520.12 NG_023308.1
Ensembl:   ENSG00000077942
Entrez:   2192
Chromosome Mapping:   22q13.31

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