PrimePCR™ Probe Assay: PARP2, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: PARP2, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: PARP2, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0051530
Assay Design:   exonic
Chromosome Location:   14:20824057-20824173question
Amplicon Length:   87
Splice Variants Targeted:   ENST00000429687 ENST00000250416 ENST00000527915 ENST00000539930

Gene Information

This gene encodes poly(ADP-ribosyl)transferase-like 2 protein which contains a catalytic domain and is capable of catalyzing a poly(ADP-ribosyl)ation reaction. This protein has a catalytic domain which is homologous to that of poly (ADP-ribosyl) transferase but lacks an N-terminal DNA binding domain which activates the C-terminal catalytic domain of poly (ADP-ribosyl) transferase. The basic residues within the N-terminal region of this protein may bear potential DNA-binding properties and may be involved in the nuclear and/or nucleolar targeting of the protein. Two alternatively spliced transcript variants encoding distinct isoforms have been found. [provided by RefSeq Jul 2008]

Gene Symbol:   PARP2
Gene Name:   poly (ADP-ribose) polymerase 2
Aliases:   ADPRT2, ADPRTL2, ADPRTL3, PARP-2, pADPRT-2
RefSeq:   NC_000014.8 NT_026437.12
Ensembl:   ENSG00000129484
Entrez:   10038
Chromosome Mapping:   14q11.2-q12

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