PrimePCR™ Probe Assay: PPP1R1B, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: PPP1R1B, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: PPP1R1B, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0051667
Assay Design:   exonic
Chromosome Location:   17:37791891-37792069question
Amplicon Length:   60
Splice Variants Targeted:   ENST00000580825 ENST00000254079 ENST00000579000 ENST00000394265 ENST00000394267

Gene Information

This gene encodes a bifunctional signal transduction molecule. Dopaminergic and glutamatergic receptor stimulation regulates its phosphorylation and function as a kinase or phosphatase inhibitor. As a target for dopamine this gene may serve as a therapeutic target for neurologic and psychiatric disorders. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq Oct 2011]

Gene Symbol:   PPP1R1B
Gene Name:   protein phosphatase 1, regulatory (inhibitor) subunit 1B
Aliases:   DARPP-32, DARPP32, FLJ20940
RefSeq:   NC_000017.10 NT_010783.15
Ensembl:   ENSG00000131771
Entrez:   84152
Chromosome Mapping:   17q12

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