PrimePCR™ Probe Assay: TDO2, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

List Price:    $263.00
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PrimePCR™ PreAmp for Probe Assay: TDO2, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: TDO2, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0052802
Assay Design:   exonic
Chromosome Location:   4:156825188-156826233question
Amplicon Length:   73
Splice Variants Targeted:   ENST00000313949 ENST00000371075 ENST00000371100 ENST00000371085 ENST00000354359 ENST00000262935 ENST00000506072 ENST00000507590 ENST00000536354 ENST00000573403 ENST00000573644 ENST00000574434

Gene Information

This gene encodes a heme enzyme that plays a critical role in tryptophan metabolism by catalyzing the first and rate-limiting step of the kynurenine pathway. Increased activity of the encoded protein and subsequent kynurenine production may also play a role in cancer through the suppression of antitumor immune responses and single nucleotide polymorphisms in this gene may be associated with autism. [provided by RefSeq Feb 2012]

Gene Symbol:   TDO2
Gene Name:   tryptophan 2,3-dioxygenase
Aliases:   TDO, TPH2, TRPO
RefSeq:   NC_000004.11 NT_016354.19 NW_003315914.1
Ensembl:   ENSG00000151790
Entrez:   6999
Chromosome Mapping:   4q31-q32

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