PrimePCR™ Probe Assay: ROR2, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: ROR2, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: ROR2, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0053867
Assay Design:   exonic
Chromosome Location:   9:94486813-94486936question
Amplicon Length:   94
Splice Variants Targeted:   ENST00000375715 ENST00000375708

Gene Information

The protein encoded by this gene is a receptor protein tyrosine kinase and type I transmembrane protein that belongs to the ROR subfamily of cell surface receptors. The protein may be involved in the early formation of the chondrocytes and may be required for cartilage and growth plate development. Mutations in this gene can cause brachydactyly type B a skeletal disorder characterized by hypoplasia/aplasia of distal phalanges and nails. In addition mutations in this gene can cause the autosomal recessive form of Robinow syndrome which is characterized by skeletal dysplasia with generalized limb bone shortening segmental defects of the spine brachydactyly and a dysmorphic facial appearance. [provided by RefSeq Jul 2008]

Gene Symbol:   ROR2
Gene Name:   receptor tyrosine kinase-like orphan receptor 2
Aliases:   BDB, BDB1, MGC163394, NTRKR2
RefSeq:   NC_000009.11 NG_008089.1 NT_008470.19
Ensembl:   ENSG00000169071
Entrez:   4920
Chromosome Mapping:   9q22

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