PrimePCR™ Probe Assay: RRM2, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: RRM2, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: RRM2, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0054111
Assay Design:   exonic
Chromosome Location:   2:10271338-10271466question
Amplicon Length:   99
Splice Variants Targeted:   ENST00000360566 ENST00000304567

Gene Information

This gene encodes one of two non-identical subunits for ribonucleotide reductase. This reductase catalyzes the formation of deoxyribonucleotides from ribonucleotides. Synthesis of the encoded protein (M2) is regulated in a cell-cycle dependent fashion. Transcription from this gene can initiate from alternative promoters which results in two isoforms that differ in the lengths of their N-termini. Related pseudogenes have been identified on chromosomes 1 and X. [provided by RefSeq Sep 2009]

Gene Symbol:   RRM2
Gene Name:   ribonucleotide reductase M2
Aliases:   R2, RR2, RR2M
RefSeq:   NC_000002.11 NT_005334.16
Ensembl:   ENSG00000171848
Entrez:   6241
Chromosome Mapping:   2p25-p24

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