PrimePCR™ Probe Assay: ANAPC2, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

List Price:    $263.00
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Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0054425
Assay Design:   exonic
Chromosome Location:   9:140082168-140082306question
Amplicon Length:   109
Splice Variants Targeted:   ENST00000323927

Gene Information

A large protein complex termed the anaphase-promoting complex (APC) or the cyclosome promotes metaphase-anaphase transition by ubiquitinating its specific substrates such as mitotic cyclins and anaphase inhibitor which are subsequently degraded by the 26S proteasome. Biochemical studies have shown that the vertebrate APC contains eight subunits. The composition of the APC is highly conserved in organisms from yeast to humans. The product of this gene is a component of the complex and shares sequence similarity with a recently identified family of proteins called cullins which may also be involved in ubiquitin-mediated degradation. [provided by RefSeq Jul 2008]

Gene Symbol:   ANAPC2
Gene Name:   anaphase promoting complex subunit 2
Aliases:   APC2, RP11-350O14.5
RefSeq:   NC_000009.11 NT_024000.16
Ensembl:   ENSG00000176248
Entrez:   29882
Chromosome Mapping:   9q34.3

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