PrimePCR™ Probe Assay: OAS2, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   Recommended - best negative control

List Price:    $263.00
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PrimePCR™ PreAmp for Probe Assay: OAS2, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: OAS2, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0058537
Assay Design:   exonic
Chromosome Location:   12:113416357-113416516question
Amplicon Length:   130
Splice Variants Targeted:   ENST00000342315 ENST00000392583 ENST00000449768 ENST00000552756

Gene Information

This gene encodes a member of the 2-5A synthetase family essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2'5'-oligoadenylates (2-5As). These molecules activate latent RNase L which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq Jul 2008]

Gene Symbol:   OAS2
Gene Name:   2'-5'-oligoadenylate synthetase 2, 69/71kDa
Aliases:   MGC78578
RefSeq:   NC_000012.11 NT_009775.17
Ensembl:   ENSG00000111335
Entrez:   4939
Chromosome Mapping:   12q24.2

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