PrimePCR™ Probe Assay: TJP2, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: TJP2, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: TJP2, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCIP0026125
Assay Design:   Intron-spanning
Chromosome Location:   9:71845137-71850994question
Amplicon Length:   142
Splice Variants Targeted:   ENST00000377245 ENST00000348208 ENST00000265384 ENST00000535702 ENST00000539225 ENST00000453658

Gene Information

This gene encodes a zonula occluden that is a member of the membrane-associated guanylate kinase homolog family. The encoded protein functions as a component of the tight junction barrier in epithelial and endothelial cells and is necessary for proper assembly of tight junctions. Mutations in this gene have been identified in patients with hypercholanemia and genomic duplication of a 270 kb region including this gene causes autosomal dominant deafness-51. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene. [provided by RefSeq Nov 2011]

Gene Symbol:   TJP2
Gene Name:   tight junction protein 2 (zona occludens 2)
Aliases:   MGC26306, X104, ZO2
RefSeq:   NC_000009.11 NT_008470.19 NG_016342.1
Ensembl:   ENSG00000119139
Entrez:   9414
Chromosome Mapping:   9q13-q21

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