PrimePCR™ Probe Assay: FGG, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: FGG, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: FGG, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCIP0026291
Assay Design:   Intron-spanning
Chromosome Location:   4:155528057-155529681question
Amplicon Length:   112
Splice Variants Targeted:   ENST00000404648 ENST00000405164 ENST00000336098 ENST00000407946

Gene Information

The protein encoded by this gene is the gamma component of fibrinogen a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading display vasoconstrictor and chemotactic activities and are mitogens for several cell types. Mutations in this gene lead to several disorders including dysfibrinogenemia hypofibrinogenemia and thrombophilia. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq Jul 2008]

Gene Symbol:   FGG
Gene Name:   fibrinogen gamma chain
Aliases:   Not Available
RefSeq:   NC_000004.11 NT_016354.19 NG_008834.1
Ensembl:   ENSG00000171557
Entrez:   2266
Chromosome Mapping:   4q28

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