PrimePCR™ Probe Assay: ANXA5, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: ANXA5, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: ANXA5, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCIP0026996
Assay Design:   Intron-spanning
Chromosome Location:   4:122591116-122592765question
Amplicon Length:   86
Splice Variants Targeted:   ENST00000296511 ENST00000512232 ENST00000501272 ENST00000515017

Gene Information

The protein encoded by this gene belongs to the annexin family of calcium-dependent phospholipid binding proteins some of which have been implicated in membrane-related events along exocytotic and endocytotic pathways. Annexin 5 is a phospholipase A2 and protein kinase C inhibitory protein with calcium channel activity and a potential role in cellular signal transduction inflammation growth and differentiation. Annexin 5 has also been described as placental anticoagulant protein I vascular anticoagulant-alpha endonexin II lipocortin V placental protein 4 and anchorin CII. The gene spans 29 kb containing 13 exons and encodes a single transcript of approximately 1.6 kb and a protein product with a molecular weight of about 35 kDa. [provided by RefSeq Jul 2008]

Gene Symbol:   ANXA5
Gene Name:   annexin A5
Aliases:   ANX5, ENX2, PP4
RefSeq:   NC_000004.11 NT_016354.19
Ensembl:   ENSG00000164111
Entrez:   308
Chromosome Mapping:   4q26-q28,4q27

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