PrimePCR™ Probe Assay: DRD2, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: DRD2, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: DRD2, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


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Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCIP0027149
Assay Design:   Intron-spanning
Chromosome Location:   11:113286246-113287609question
Amplicon Length:   83
Splice Variants Targeted:   ENST00000346454 ENST00000362072 ENST00000544518 ENST00000542968 ENST00000538967 ENST00000355319

Gene Information

This gene encodes the D2 subtype of the dopamine receptor. This G-protein coupled receptor inhibits adenylyl cyclase activity. A missense mutation in this gene causes myoclonus dystonia; other mutations have been associated with schizophrenia. Alternative splicing of this gene results in two transcript variants encoding different isoforms. A third variant has been described but it has not been determined whether this form is normal or due to aberrant splicing. [provided by RefSeq Jul 2008]

Gene Symbol:   DRD2
Gene Name:   dopamine receptor D2
Aliases:   D2DR, D2R
RefSeq:   NC_000011.9 NG_008841.1 NT_033899.8
Ensembl:   ENSG00000149295
Entrez:   1813
Chromosome Mapping:   11q23

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