PrimePCR™ Probe Assay: TXNRD2, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

List Price:    $263.00
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PrimePCR™ PreAmp for Probe Assay: TXNRD2, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: TXNRD2, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCIP0027709
Assay Design:   Intron-spanning
Chromosome Location:   22:19898902-19903293question
Amplicon Length:   107
Splice Variants Targeted:   ENST00000400518 ENST00000400521 ENST00000400525 ENST00000400519 ENST00000538798 ENST00000535882 ENST00000542719 ENST00000540474 ENST00000334363

Gene Information

Thioredoxin reductase (TR) is a dimeric NADPH-dependent FAD containing enzyme that catalyzes the reduction of the active site disulfide of thioredoxin and other substrates. TR is a member of a family of pyridine nucleotide-disulfide oxidoreductases and is a key enzyme in the regulation of the intracellular redox environment. Three thioredoxin reductase genes have been found that encode selenocysteine containing proteins. This gene partially overlaps the COMT gene on chromosome 22. [provided by RefSeq Jul 2008]

Gene Symbol:   TXNRD2
Gene Name:   thioredoxin reductase 2
Aliases:   SELZ, TR, TR-BETA, TR3, TRXR2
RefSeq:   NG_011526.1 NC_000022.10 NG_011835.1 NT_011519.10
Ensembl:   ENSG00000184470
Entrez:   10587
Chromosome Mapping:   22q11.21

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