PrimePCR™ Probe Assay: HDAC6, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: HDAC6, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: HDAC6, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCIP0029652
Assay Design:   Intron-spanning
Chromosome Location:   X:48661553-48664777question
Amplicon Length:   169
Splice Variants Targeted:   ENST00000334136 ENST00000376619 ENST00000441703 ENST00000426196 ENST00000443563 ENST00000440653 ENST00000444343 ENST00000436813 ENST00000413163 ENST00000376643 ENST00000376610

Gene Information

Histones play a critical role in transcriptional regulation cell cycle progression and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription. [provided by RefSeq Jul 2008]

Gene Symbol:   HDAC6
Gene Name:   histone deacetylase 6
Aliases:   FLJ16239, HD6
RefSeq:   NC_000023.10 NG_012560.1 NT_079573.4
Ensembl:   ENSG00000094631
Entrez:   10013
Chromosome Mapping:   Xp11.23

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