PrimePCR™ Probe Assay: CDH3, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: CDH3, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: CDH3, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


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Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCIP0029867
Assay Design:   Intron-spanning
Chromosome Location:   16:68719201-68721501question
Amplicon Length:   110
Splice Variants Targeted:   ENST00000264012 ENST00000429102 ENST00000542274

Gene Information

This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene have been associated with congential hypotrichosis with juvenile macular dystrophy. [provided by RefSeq Jul 2008]

Gene Symbol:   CDH3
Gene Name:   cadherin 3, type 1, P-cadherin (placental)
Aliases:   CDHP, HJMD, PCAD
RefSeq:   NC_000016.9 NG_009096.1 NT_010498.15
Ensembl:   ENSG00000062038
Entrez:   1001
Chromosome Mapping:   16q22.1

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