PrimePCR™ Probe Assay: XRCC4, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

List Price:    $263.00
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PrimePCR™ PreAmp for Probe Assay: XRCC4, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: XRCC4, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCIP0030367
Assay Design:   Intron-spanning
Chromosome Location:   5:82406874-82491618question
Amplicon Length:   149
Splice Variants Targeted:   ENST00000338635 ENST00000396027 ENST00000511817 ENST00000282268 ENST00000514538

Gene Information

The protein encoded by this gene functions together with DNA ligase IV and the DNA-dependent protein kinase in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. The non-homologous end-joining pathway is required both for normal development and for suppression of tumors. This gene functionally complements XR-1 Chinese hamster ovary cell mutant which is impaired in DNA double-strand breaks produced by ionizing radiation and restriction enzymes. Alternative transcription initiation and alternative splicing generates several transcript variants. [provided by RefSeq Sep 2008]

Gene Symbol:   XRCC4
Gene Name:   X-ray repair complementing defective repair in Chinese hamster cells 4
Aliases:   Not Available
RefSeq:   NC_000005.9 NT_006713.15
Ensembl:   ENSG00000152422
Entrez:   7518
Chromosome Mapping:   5q14.2

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