PrimePCR™ Probe Assay: CRKL, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: CRKL, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: CRKL, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCIP0031273
Assay Design:   Intron-spanning
Chromosome Location:   22:21288438-21304050question
Amplicon Length:   117
Splice Variants Targeted:   ENST00000354336

Gene Information

This gene encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase plays a role in fibroblast transformation by BCR-ABL and may be oncogenic.[provided by RefSeq Jan 2009]

Gene Symbol:   CRKL
Gene Name:   v-crk sarcoma virus CT10 oncogene homolog (avian)-like
Aliases:   Not Available
RefSeq:   NC_000022.10 NG_016354.1 NT_011520.12
Ensembl:   ENSG00000099942
Entrez:   1399
Chromosome Mapping:   22q11,22q11.21

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