PrimePCR™ lncRNA® Probe Assay:HTR2A, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression.

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   Same primer pair as used in SYBR assay qhsaLED0104209

List Price:    $254.00
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PrimePCR™ IncRNA PreAmp for Probe Assay: HTR2A, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ IncRNA Template for Probe Assay: HTR2A, Human
Reaction:     4 billion copies/200 µl
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   lncRNA Expression
Unique Assay ID:   qhsaLEP0181449
Assay Design:   exonic
Chromosome Location:   chr13:46892401-46892550question
Amplicon Length:   120
Refseq Transcripts Amplified:   NM_001165947,NM_000621
Splice Variants Targeted:   ENST00000378688 ENST00000542664 ENST00000543956
LNCipedia Splice Variants Targeted:   lnc-ESD-2:1

Gene Information

This gene encodes one of the receptors for serotonin a neurotransmitter with many roles. Mutations in this gene are associated with susceptibility to schizophrenia and obsessive-compulsive disorder and are also associated with response to the antidepressant citalopram in patients with major depressive disorder (MDD). MDD patients who also have a mutation in intron 2 of this gene show a significantly reduced response to citalopram as this antidepressant downregulates expression of this gene. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq Sep 2009]

Gene Symbol:   HTR2A
Gene Name:   5-hydroxytryptamine (serotonin) receptor 2A
Aliases:   5-HT2A, HTR2
RefSeq:   NC_000013.10 NG_013011.1 NT_024524.14
Ensembl:   ENSG00000102468
LNCipedia:   lnc-ESD-2
Entrez:   3356
Chromosome Mapping:   13q14-q21
Gene Strand:   Not Available

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