PrimePCR™ Probe Assay: Cp, Mouse

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: Cp, Mouse
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: Cp, Mouse
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qMmuCEP0053798
Assay Design:   exonic
Chromosome Location:   3:19987456-19987574question
Amplicon Length:   89
Splice Variants Targeted:   ENSMUST00000091309 ENSMUST00000003714 ENSMUST00000108328 ENSMUST00000108325 ENSMUST00000172860 ENSMUST00000108329

Gene Information

The protein encoded by this gene is a copper-containing glycoprotein found soluble in the serum and GPI-anchored in other tissues. It oxidizes Fe(II) to Fe(III) and is proposed to play an important role in iron homeostasis. In humans mutations of this gene cause aceruloplasminemia which is characterized by retinal degeneration diabetes anemia and neurological symptoms. In mouse deficiency of this gene in combination with a deficiency of its homolog hephaestin causes retinal degeneration and serves as a pathophysiological model for aceruloplasminemia and age-related macular degeneration. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq Jan 2013]

Gene Symbol:   Cp
Gene Name:   Ceruloplasmin
Aliases:   D3Ertd555e
RefSeq:   NC_000069.6 NT_162143.4
Ensembl:   ENSMUSG00000003617
Entrez:   12870
Chromosome Mapping:   3|3 D

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