Gene:  COL1A1, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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This gene encodes the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone cornea dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV Ehlers-Danlos syndrome type VIIA Ehlers-Danlos syndrome Classical type Caffey Disease and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22 where this gene and the gene for platelet-derived growth factor beta are located are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans resulting from unregulated expression of the growth factor. Two transcripts resulting from the use of alternate polyadenylation signals have been identified for this gene. [provided by R. Dalgleish Feb 2008]

PrimePCR™ SYBR® Green Assay: COL1A1, Rhesus Monkey
Collagen, type I, alpha 1

Assay Type: SYBR® Green
Assay Design: Exonic
Application: Gene Expression
Unique Assay ID: qMccCED0006115
List Price:    $111.00
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PrimePCR™ Probe Assay: COL1A1, Rhesus Monkey
Collagen, type I, alpha 1

Assay Type: Probe
Assay Design: Exonic
Application: Gene Expression
Unique Assay ID: qMccCEP0026299
List Price:    $214.00
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