Gene:  GSTM3, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha kappa mu omega pi sigma theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds including carcinogens therapeutic drugs environmental toxins and products of oxidative stress by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Mutations of this class mu gene have been linked with a slight increase in a number of cancers likely due to exposure with environmental toxins. Alternative splicing results in multiple transcript variants. [provided by RefSeq Nov 2008]

PrimePCR™ SYBR® Green Assay: GSTM3, Human
glutathione S-transferase mu 3 (brain)

Assay Type: SYBR® Green
Assay Design: Exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0001288
List Price:    $174.00
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PrimePCR™ SYBR® Green Assay: GSTM3, Human
glutathione S-transferase mu 3 (brain)

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0044540
Info:   Same primer pair as used in probe assay qHsaCEP0051802
List Price:    $174.00
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PrimePCR™ Probe Assay: GSTM3, Human
glutathione S-transferase mu 3 (brain)

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0051802
List Price:    $255.00
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