Gene:  PEX19, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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This gene is necessary for early peroxisomal biogenesis. It acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs). Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive lethal diseases characterized by multiple defects in peroxisome function. These disorders have at least 14 complementation groups with more than one phenotype being observed for some complementation groups. Although the clinical features of PBD patients vary cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause of Zellweger syndrome (ZWS) as well as peroxisome biogenesis disorder complementation group 14 (PBD-CG14) which is also known as PBD-CGJ. Alternative splicing results in multiple transcript variants. [provided by RefSeq Aug 2010]

PrimePCR™ SYBR® Green Assay: PEX19, Yeast
Chaperone and import receptor for newly-synthesized class I peroxisomal membrane proteins (PMPs), binds PMPs in the cytoplasm and delivers them to the peroxisome for subsequent insertion into the peroxisomal membrane

Assay Type: SYBR® Green
Assay Design: Exonic
Application: Gene Expression
Unique Assay ID: qSceCED0004600
List Price:    $137.00
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PrimePCR™ Probe Assay: PEX19, Yeast
Chaperone and import receptor for newly-synthesized class I peroxisomal membrane proteins (PMPs), binds PMPs in the cytoplasm and delivers them to the peroxisome for subsequent insertion into the peroxisomal membrane

Assay Type: Probe
Assay Design: Exonic
Application: Gene Expression
Unique Assay ID: qSceCEP0011172
List Price:    $263.00
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