Gene:  PLOD2, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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The protein encoded by this gene is a membrane-bound homodimeric enzyme that is localized to the cisternae of the rough endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VIB have deficiencies in lysyl hydroxylase activity. Mutations in the coding region of this gene are associated with Bruck syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq Jul 2008]

PrimePCR™ SYBR® Green Assay: PLOD2, Human
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0045587
Info:   Recommended - best efficiency; Same primer pair as used in probe assay qHsaCEP0052848
List Price:    $146.00
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PrimePCR™ SYBR® Green Assay: PLOD2, Human
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0006833
List Price:    $146.00
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PrimePCR™ Probe Assay: PLOD2, Human
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0052848
List Price:    $214.00
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    Related pathways not available
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