Multiple myeloma

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Disease State Panels

PrimePCR disease state panels were designed by referencing the National Library of Medicine database. Disease state panels allow for the thorough investigation of differentially expressed genes within a specified pathology.

Gene targets for each disease state were ranked and compared according to the following criteria:

Frequency of gene expression changes in biomarker studies
Popularity in overall medical research
Popularity in current medical research

The resulting gene scores were used to design real-time PCR panels. For diseases with a large number of gene targets, multiple tiered plates are available. Tier 1 plates represent the highest ranked targets with subsequent tiers containing the lower ranked or less well characterized targets.

Target Details

Click on a target from the pathway image to view related information.

Terms and Conditions

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GeneCode	Multiple myeloma Tier 1 H96	Multiple myeloma Tier 2 H96	Multiple myeloma H384
ABCB1	✓	✗	✓
ABCG2	✓	✗	✓
ACVR2A	✗	✓	✓
AIFM1	✗	✓	✓
ALOX5	✓	✗	✓
ANGPT1	✓	✗	✓
ANGPT2	✓	✗	✓
ANXA1	✓	✗	✓
APAF1	✗	✓	✓
ATF3	✓	✗	✓
ATP11B	✗	✓	✓
AURKA	✓	✗	✓
BAMBI	✓	✗	✓
BCL10	✗	✓	✓
BCL11A	✓	✗	✓
BCL2	✓	✗	✓
BCL2A1	✗	✓	✓
BCL3	✓	✗	✓
BHLHE40	✓	✗	✓
BID	✓	✗	✓
BIRC2	✗	✓	✓
BIRC3	✓	✗	✓
BIRC5	✓	✗	✓
BMP2	✓	✗	✓
BMP4	✓	✗	✓
BMP6	✗	✓	✓
BMPR1A	✗	✓	✓
BMPR1B	✗	✓	✓
BMPR2	✗	✓	✓
BNIP3	✗	✓	✓
BSG	✗	✓	✓
BUB1	✓	✗	✓
C12orf11	✗	✓	✓
C13orf15	✓	✗	✓
CALM1	✓	✗	✓
CALM2	✓	✗	✓
CALM3	✓	✗	✓
CASP3	✓	✗	✓
CASP6	✓	✗	✓
CASP8	✓	✗	✓
CASP9	✓	✗	✓
CCND3	✓	✗	✓
CCNE2	✗	✓	✓
CCR7	✗	✓	✓
CCT3	✗	✓	✓
CD200	✗	✓	✓
CD83	✗	✓	✓
CDC42	✓	✗	✓
CDK1	✓	✗	✓
CDKN2C	✓	✗	✓
CHD2	✗	✓	✓
CITED2	✓	✗	✓
CPSF6	✗	✓	✓
CRBN	✗	✓	✓
CSNK1A1	✗	✓	✓
CXCR4	✓	✗	✓
DBF4	✗	✓	✓
DDX5	✓	✗	✓
DEPTOR	✗	✓	✓
DKC1	✗	✓	✓
DLGAP5	✓	✗	✓
DNMT1	✓	✗	✓
DNMT3A	✗	✓	✓
DNMT3B	✓	✗	✓
DTL	✓	✗	✓
DUSP1	✓	✗	✓
DUSP6	✗	✓	✓
EFNB2	✗	✓	✓
EGFR	✓	✗	✓
EGR1	✓	✗	✓
EGR3	✗	✓	✓
ELL2	✗	✓	✓
EPHB4	✗	✓	✓
EXT1	✗	✓	✓
FADD	✗	✓	✓
FAF1	✗	✓	✓
FASN	✓	✗	✓
FCRL2	✗	✓	✓
FGFR3	✗	✓	✓
FKBP5	✓	✗	✓
FOS	✓	✗	✓
FOSB	✓	✗	✓
FOXO1	✓	✗	✓
G3BP1	✗	✓	✓
GADD45B	✓	✗	✓
GAPDH	✓	✗	✓
GLB1	✗	✓	✓
GPI	✗	✓	✓
H3F3A	✗	✓	✓
H3F3B	✗	✓	✓
HBB	✓	✗	✓
HIST1H1C	✗	✓	✓
HIST2H2BE	✗	✓	✓
HMMR	✓	✗	✓
HNRNPC	✗	✓	✓
HOXB7	✓	✗	✓
HPRT1	✓	✗	✓
HPSE	✗	✓	✓
HS3ST2	✓	✗	✓
HSPA1A	✓	✗	✓
HSPA1B	✓	✗	✓
HSPA4	✓	✗	✓
HSPA9	✓	✗	✓
ID1	✓	✗	✓
ID2	✓	✗	✓
IDH1	✓	✗	✓
IER2	✗	✓	✓
IFIH1	✗	✓	✓
IGJ	✗	✓	✓
IL7R	✗	✓	✓
IRF8	✓	✗	✓
KCTD12	✓	✗	✓
KIF11	✗	✓	✓
KIF20A	✗	✓	✓
KLF2	✗	✓	✓
KLF4	✓	✗	✓
KLF9	✗	✓	✓
KRAS	✓	✗	✓
LGALS1	✓	✗	✓
LYZ	✗	✓	✓
MAGEA1	✗	✓	✓
MAGEA2	✗	✓	✓
MAGEC2	✗	✓	✓
MAPKAPK2	✗	✓	✓
MCL1	✓	✗	✓
MELK	✓	✗	✓
MPO	✗	✓	✓
MT1X	✗	✓	✓
MVP	✗	✓	✓
MYC	✓	✗	✓
MYCN	✗	✓	✓
NBEA	✗	✓	✓
NFKBIA	✓	✗	✓
NME1	✓	✗	✓
NOD2	✗	✓	✓
NUF2	✗	✓	✓
NUSAP1	✓	✗	✓
PAICS	✓	✗	✓
PDE4B	✗	✓	✓
PIM2	✗	✓	✓
PLAU	✓	✗	✓
PNP	✗	✓	✓
PTEN	✓	✗	✓
PTGS2	✓	✗	✓
PTK2	✓	✗	✓
PTP4A3	✗	✓	✓
PTX3	✗	✓	✓
RAD51	✗	✓	✓
RAN	✗	✓	✓
RANBP2	✗	✓	✓
RARA	✓	✗	✓
RRM2	✓	✗	✓
RRP1B	✗	✓	✓
S100A8	✓	✗	✓
SLC39A8	✗	✓	✓
SMAD6	✗	✓	✓
SPTBN1	✓	✗	✓
SRGN	✗	✓	✓
SS18	✗	✓	✓
SSBP1	✓	✗	✓
SUB1	✗	✓	✓
SULF2	✗	✓	✓
TBP	✓	✗	✓
TCERG1	✗	✓	✓
THBS1	✓	✗	✓
TMED10	✗	✓	✓
TMEM147	✗	✓	✓
TNFRSF10A	✗	✓	✓
TNFRSF10B	✗	✓	✓
TNFRSF17	✗	✓	✓
TNFSF10	✓	✗	✓
TOP1	✗	✓	✓
TOP2A	✓	✗	✓
TRIAP1	✗	✓	✓
TUBB2A	✗	✓	✓
TXN	✓	✗	✓
TXNIP	✓	✗	✓
UHRF1	✗	✓	✓
VDAC1	✗	✓	✓
VEGFA	✓	✗	✓
WHSC1	✗	✓	✓
WT1	✗	✓	✓
XBP1	✓	✗	✓
XIAP	✓	✗	✓
ZEB2	✓	✗	✓
ZFP36L1	✗	✓	✓
ZHX2	✗	✓	✓

GeneCode	Multiple myeloma Tier 1 M96	Multiple myeloma Tier 2 M96	Multiple myeloma M384
Abcb1a	✓	✗	✓
Abcg2	✓	✗	✓
Acvr2a	✗	✓	✓
Aifm1	✗	✓	✓
Alox5	✓	✗	✓
Angpt1	✓	✗	✓
Angpt2	✓	✗	✓
Anxa1	✓	✗	✓
Apaf1	✗	✓	✓
Atf3	✓	✗	✓
Atp11b	✗	✓	✓
Aurka	✓	✗	✓
Bambi	✓	✗	✓
Bcl10	✗	✓	✓
Bcl11a	✓	✗	✓
Bcl2	✓	✗	✓
Bcl2a1a	✗	✓	✓
Bcl3	✓	✗	✓
Bhlhe40	✓	✗	✓
Bid	✓	✗	✓
Birc2	✓	✗	✓
Birc3	✓	✗	✓
Birc5	✓	✗	✓
Blnk	✗	✓	✓
Bmp2	✓	✗	✓
Bmp4	✓	✗	✓
Bmp6	✗	✓	✓
Bmpr1a	✗	✓	✓
Bmpr1b	✗	✓	✓
Bmpr2	✗	✓	✓
Bnip3	✓	✗	✓
Bsg	✗	✓	✓
Bub1	✓	✗	✓
C1qbp	✗	✓	✓
Calm1	✓	✗	✓
Casp3	✓	✗	✓
Casp6	✓	✗	✓
Casp8	✓	✗	✓
Casp9	✓	✗	✓
Ccnd3	✓	✗	✓
Ccne2	✗	✓	✓
Ccr7	✗	✓	✓
Cct3	✗	✓	✓
Cd200	✗	✓	✓
Cd83	✗	✓	✓
Cdc42	✓	✗	✓
Cdk1	✓	✗	✓
Cdkn2c	✓	✗	✓
Chd2	✗	✓	✓
Cited2	✓	✗	✓
Cpsf6	✗	✓	✓
Crbn	✗	✓	✓
Csnk1a1	✗	✓	✓
Cxcr4	✓	✗	✓
Dbf4	✗	✓	✓
Ddx5	✓	✗	✓
Deptor	✓	✗	✓
Dkc1	✗	✓	✓
Dlgap5	✓	✗	✓
Dnmt1	✓	✗	✓
Dnmt3a	✓	✗	✓
Dnmt3b	✓	✗	✓
Dtl	✓	✗	✓
Dusp1	✓	✗	✓
Dusp6	✗	✓	✓
Efnb2	✗	✓	✓
Egfr	✓	✗	✓
Egr1	✓	✗	✓
Egr3	✗	✓	✓
Ell2	✗	✓	✓
Ephb4	✗	✓	✓
Etnk1	✗	✓	✓
Ext1	✗	✓	✓
Fadd	✗	✓	✓
Faf1	✗	✓	✓
Fasn	✓	✗	✓
Fgfr3	✗	✓	✓
Fignl1	✗	✓	✓
Fkbp5	✓	✗	✓
Flt3	✗	✓	✓
Fos	✓	✗	✓
Fosb	✓	✗	✓
Foxo1	✓	✗	✓
G3bp1	✗	✓	✓
Gadd45b	✓	✗	✓
Gapdh	✓	✗	✓
Glb1	✗	✓	✓
Gpi1	✗	✓	✓
H3f3a	✓	✗	✓
Hist1h1c	✗	✓	✓
Hist1h2bc	✗	✓	✓
Hmmr	✓	✗	✓
Hnrnpc	✗	✓	✓
Hoxb7	✓	✗	✓
Hprt	✓	✗	✓
Hpse	✗	✓	✓
Hs3st2	✓	✗	✓
Hspa1a	✓	✗	✓
Hspa4	✓	✗	✓
Hspa9	✓	✗	✓
Id1	✓	✗	✓
Id2	✓	✗	✓
Idh1	✓	✗	✓
Ier2	✗	✓	✓
Ifih1	✗	✓	✓
Igj	✗	✓	✓
Il7r	✗	✓	✓
Irf8	✓	✗	✓
Kif11	✗	✓	✓
Kif20a	✗	✓	✓
Klf2	✗	✓	✓
Klf4	✓	✗	✓
Klf9	✗	✓	✓
Kras	✓	✗	✓
Lgals1	✓	✗	✓
Lsm5	✗	✓	✓
Lyz1	✓	✗	✓
Mapkapk2	✗	✓	✓
Mcl1	✓	✗	✓
Melk	✓	✗	✓
Mpo	✗	✓	✓
Ms4a6d	✗	✓	✓
Mvp	✗	✓	✓
Myc	✓	✗	✓
Mycn	✓	✗	✓
Nbea	✗	✓	✓
Nfkbia	✓	✗	✓
Nme1	✓	✗	✓
Nod2	✗	✓	✓
Nog	✗	✓	✓
Nuf2	✗	✓	✓
Nusap1	✓	✗	✓
Paics	✓	✗	✓
Pde4b	✗	✓	✓
Pim2	✗	✓	✓
Plau	✓	✗	✓
Pnp	✗	✓	✓
Prg2	✗	✓	✓
Pten	✓	✗	✓
Ptgs2	✓	✗	✓
Ptk2	✓	✗	✓
Ptp4a3	✗	✓	✓
Ptx3	✗	✓	✓
Rad51	✗	✓	✓
Ran	✗	✓	✓
Ranbp2	✗	✓	✓
Rara	✓	✗	✓
Rcn2	✗	✓	✓
Rgs18	✗	✓	✓
Rhoh	✗	✓	✓
Rrm2	✓	✗	✓
Rrp1b	✗	✓	✓
S100a8	✓	✗	✓
Slc39a8	✗	✓	✓
Smad5	✗	✓	✓
Smad6	✗	✓	✓
Srgn	✗	✓	✓
Ss18	✗	✓	✓
Ssbp1	✓	✗	✓
Sub1	✗	✓	✓
Sulf2	✗	✓	✓
Tbp	✓	✗	✓
Tcerg1	✗	✓	✓
Thbs1	✓	✗	✓
Tmem147	✗	✓	✓
Tmem57	✗	✓	✓
Tnfrsf10b	✗	✓	✓
Tnfrsf17	✗	✓	✓
Tnfsf10	✓	✗	✓
Tnfsf13b	✗	✓	✓
Top1	✗	✓	✓
Top2a	✓	✗	✓
Triap1	✗	✓	✓
Tubb2a	✗	✓	✓
Txn1	✓	✗	✓
Txnip	✓	✗	✓
Uhrf1	✗	✓	✓
Vdac1	✗	✓	✓
Vegfa	✓	✗	✓
Whsc1	✗	✓	✓
Wt1	✗	✓	✓
Xbp1	✓	✗	✓
Xiap	✓	✗	✓
Zeb2	✓	✗	✓
Zfp36l1	✗	✓	✓
Zfp451	✗	✓	✓
Zhx2	✗	✓	✓

GeneCode	Multiple Myeloma R96	Multiple Myeloma R384
Abcb1a	✓	✓
Abcg2	✓	✓
Acvr2a	✗	✓
Aifm1	✗	✓
Alox5	✓	✓
Angpt1	✓	✓
Angpt2	✓	✓
Anxa1	✓	✓
Atf3	✓	✓
Aurka	✓	✓
Bambi	✓	✓
Bcl11a	✓	✓
Bcl2	✓	✓
Bcl2a1	✗	✓
Bcl3	✓	✓
Bhlhe40	✓	✓
Bid	✓	✓
Birc2	✓	✓
Birc3	✓	✓
Birc5	✓	✓
Bmp2	✓	✓
Bmp4	✓	✓
Bmpr1a	✗	✓
Bmpr2	✗	✓
Bnip3	✓	✓
Bub1	✓	✓
Casp3	✓	✓
Casp6	✓	✓
Casp8	✓	✓
Casp9	✓	✓
Ccnd3	✓	✓
Ccne2	✗	✓
Ccr7	✗	✓
Cct3	✗	✓
Cd200	✗	✓
Cdc42	✓	✓
Cdk1	✓	✓
Cdkn2c	✓	✓
Cited2	✓	✓
Cxcr4	✓	✓
Ddx5	✓	✓
Dlgap5	✓	✓
Dnmt1	✓	✓
Dnmt3a	✓	✓
Dnmt3b	✓	✓
Dtl	✓	✓
Dusp1	✓	✓
Dusp6	✗	✓
Efnb2	✗	✓
Egfr	✓	✓
Egr1	✓	✓
Egr3	✗	✓
Fadd	✗	✓
Fasn	✓	✓
Fgfr3	✗	✓
Fkbp5	✓	✓
Fos	✓	✓
Fosb	✓	✓
Foxo1	✓	✓
G3bp1	✗	✓
Gadd45b	✓	✓
Gapdh	✓	✓
Gpi	✗	✓
H3f3b	✓	✓
HBB	✓	✓
Hbb	✓	✓
Hbb-b1	✓	✓
Hnrnpc	✗	✓
Hoxb7	✓	✓
Hprt1	✓	✓
Hpse	✗	✓
Hs3st2	✓	✓
Hspa4	✓	✓
Hspa9	✓	✓
Id1	✓	✓
Id2	✓	✓
Idh1	✓	✓
Ifih1	✗	✓
Irf8	✓	✓
Kif11	✗	✓
Kif20a	✗	✓
Klf2	✗	✓
Klf4	✓	✓
Klf9	✗	✓
Kras	✓	✓
Lgals1	✓	✓
Lyz2	✓	✓
Melk	✓	✓
Mpo	✗	✓
Mvp	✗	✓
Myc	✓	✓
Mycn	✓	✓
Nfkbia	✓	✓
Nme1	✓	✓
Nusap1	✓	✓
Paics	✓	✓
Plau	✓	✓
Pnp	✗	✓
Pten	✓	✓
Ptgs2	✓	✓
Ptk2	✓	✓
Ptx3	✗	✓
Rara	✓	✓
Rgcc	✓	✓
Rrm2	✓	✓
RRM2	✓	✓
Rrp1b	✗	✓
S100a8	✓	✓
Sptbn1	✓	✓
Ss18	✗	✓
Ssbp1	✓	✓
SUB1	✗	✓
Tbp	✓	✓
Tnfrsf17	✗	✓
Tnfsf10	✓	✓
Top2a	✓	✓
Tubb2a	✗	✓
Txn1	✓	✓
Txnip	✓	✓
Vegfa	✓	✓
Xbp1	✓	✓
Xiap	✓	✓
Zeb2	✓	✓